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T14496 |
BAMB-4
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ITPKA-IN-C14 |
Others
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BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in... |
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T12302 |
OMDM-1
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(Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide |
Endogenous Metabolite
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OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. |
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T12306 |
OMDM-5
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Cannabinoid Receptor
,
Endogenous Metabolite
,
TRP/TRPV Channel
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OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). |
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T12307 |
OMDM-6
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Cannabinoid Receptor
,
Endogenous Metabolite
,
TRP/TRPV Channel
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OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM. |
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T11820 |
LAT1-IN-1
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BCH |
Apoptosis
,
Others
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LAT1-IN-1 (BCH) (BCH) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis. is a selective and competitive inhibitor of large neutral... |
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T41008 |
BODIPY-Cholesterol
|
BCh2 |
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BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake ... |
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T67981 |
Copper histidine
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Copper histidine inhibited Ctr1-mediated cellular uptake of oxaliplatin in vitro without altering oxaliplatin accumulation of platinum or neurotoxicity in DRG tissues in vivo. Copper histidine is administered orally for ... |
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T20067 |
WST-1
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WST 1 |
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WST-1 is a cytotoxic, water-soluble tetrazolium salt that induces intracellular mitochondrial dehydrogenases to undergo NADH-dependent enzymatic reactions, releasing water-soluble methylbenzene products.WST-1 can be used... |
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TQ0081 |
JPH203
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KYT-0353 |
Others
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JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-infl... |
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T9108 |
BI-0115
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Lipoxygenase
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BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX... |
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T12304 |
OMDM-3
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Others
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OMDM-3 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 16.6 μM). |
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T12305 |
OMDM-4
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Others
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OMDM-4 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 17.7 μM). |
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T12303 |
OMDM-2
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Others
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OMDM-2 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 3.0 μM). |
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T26635 |
Antifolate C1
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AGF 94,AGF94,AGF-94 |
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Antifolate C1 is an inhibitor of de novo purine biosynthesis. Antifolate C1 has selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter (PCFT) over the reduced folate c... |
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T69385 |
Baicalein monohydrate
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Baicalein monohydrate is an inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. |
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T37373 |
4-hydroxy-3-Methoxyphenylglycol (piperazine salt)
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4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermedi... |
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T78664 |
Biotin-labeled ODN 1826 sodium
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|
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Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and localization through biotin detection systems and light micro... |
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T78995 |
Biotin-labeled ODN 2088 sodium
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|
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Biotin-labeled ODN 2088 (sodium) acts as a potent inhibitor of TLR3, TLR7, and TLR9. It is utilized to assess cellular uptake and localization of CpG ODN through a biotin detection system coupled with light microscopy. |
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T78990 |
Biotin-labeled ODN 1018 sodium
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Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through biotin detection systems and light microscopy. |
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T72988 |
PhotoCORM-2
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photoCORM-2 is a single carbon monoxide releasing molecule (CORM). photoCORM-2 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-2 has anti-tumor activity... |
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T78991 |
Biotin-labeled ODN 1585 sodium
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Biotin-labeled ODN 1585 (sodium) serves as a potent inducer of IFN and TNFα production and facilitates the assessment of CpG ODN cellular uptake and localization through detection with a biotin system and light microscop... |
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T78089 |
FITC-labeled ODN 1018 sodium
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FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm)... |
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T78999 |
Biotin-labeled ODN 2395 sodium
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Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin detection system coupled with light microscopy. |
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T78662 |
Biotin-labeled Agatolimod sodium
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|
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Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of CpG ODNs through a biotin detection system with light micro... |
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T78993 |
Biotin-labeled ODN 1668 sodium
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|
|
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Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of CpG ODNs via a biotin detection system and light microscopy. |
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T79001 |
Biotin-labeled ODN TTAGGG sodium
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|
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Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS. It serves as a tool for assessing cellular uptake and localization of CpG ODN using bioti... |
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T78998 |
FITC-labeled ODN 2216 sodium
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FITC-labeled ODN 2216 (sodium), a specific agonist for human toll-like receptor 9 (TLR9), facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 ... |
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T82524 |
Dual photoCORM 1
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|
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Dual photoCORM 1 (compound 5), a metal-free, photoactive, dual carbon monoxide releasing molecule (CORM), demonstrates efficient cellular uptake and enables real-time tracking of CO release via a colorimetric change in B... |
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T78997 |
Biotin-labeled ODN 2216 sodium
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|
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Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and localization through a biotin detection system coupled with ... |
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T81035 |
TAT-NSF222 Fusion Peptide
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TAT-NSF222 Fusion Peptide is a bifunctional polypeptide comprising a TAT domain, facilitating cellular uptake via macropinocytosis, and an NSF domain, which acts as an inhibitor of N-ethylmaleimide-sensitive factor (NSF)... |
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T72987 |
PhotoCORM-1
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|
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photoCORM-1 is a combinatorial carbon monoxide releasing molecule (CORM). photoCORM-1 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-1 has anti-tumor a... |
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T78992 |
FITC-labeled ODN 1585 sodium
|
|
|
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FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or ... |
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T78752 |
Antibacterial agent 145
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Compound 1b, also known as Antibacterial agent 145, targets the bacterial iron uptake pathway to exert its effects. It compromises the integrity of the bacterial cytoplasmic membrane and inhibits cellular metabolism whil... |
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T78663 |
FITC-labeled Agatolimod sodium
|
|
|
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FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization via confocal laser-scanning microscopy (excitation 495 n... |
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T79000 |
FITC-labeled ODN 2395 sodium
|
|
|
|
FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emiss... |
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T78665 |
FITC-labeled ODN 1826 sodium
|
|
|
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FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495... |
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T78994 |
FITC-labeled ODN 1668 sodium
|
|
|
|
FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist. This compound is utilized to assess the cellular uptake and localization of CpG ODNs using techniques such as confoca... |
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T78996 |
FITC-labeled ODN 2088 sodium
|
|
|
|
FITC-labeled ODN 2088 (sodium) serves as a potent inhibitor of TLR3, TLR7, and TLR9, and is utilized to assess CpG ODN cellular uptake and localization utilizing confocal laser-scanning microscopy (excitation 495 nm, emi... |
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T79002 |
FITC-labeled ODN TTAGGG sodium
|
|
|
|
FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS. This compound facilitates the assessment of CpG ODN cellular uptake and localization via confocal... |
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T60858 |
MOPIPP
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|
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MOPIPP is a novel indolebased chalcone that can cross the blood-brain barrier. MOPIPP inhibits the tumor progression agaisnt glioblastoma cells. MOPIPP induces cellular vacuolization as well as increases autophagosomes n... |
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T38070 |
Arachidonic Acid-biotin
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|
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Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate f... |
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T78041 |
Tat-peptide control 168-189 TFA
|
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Tat-peptide 168-189, a cell-permeable, Tat-labeled fusion peptide derived from residues 168-189 of rat G3BP1, features the HIV Tat sequence at its least conserved terminus to enhance cellular uptake. It serves as the neg... |
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T28398 |
Phenanthriplatin
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cis-[Pt(NH3)2-(phenanthridine)Cl]NO3 |
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Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin A... |
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T76546 |
TAT-HA2 Fusion Peptide
|
|
|
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TAT-HA2 Fusion Peptide, a peptide-based delivery agent, synergizes the pH-sensitive HA2 fusion peptide from Influenza with the cell-penetrating peptide TAT from HIV. This compound facilitates the cellular uptake of macro... |
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T82108 |
ICMT-IN-35
|
|
|
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ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative. It demonstrates cellular uptake by mammalian cells, disrupts K-Ras membrane association, and induces K-Ras misloca... |
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T80226 |
R8 Bid BH3
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r8 Bid BH3, a biologically active peptide, is a pro-apoptotic member of the "BH3-only" subset within the BCL-2 family proteins, pivotal in regulating apoptosis. This compound exhibits lethality towards Bcl-2-expressing h... |
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T36424 |
DSPE-PEG(2000)-amine (sodium salt)
|
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|
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DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3D... |
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T83922 |
Pep2 Peptide
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Pep2 peptide, a peptide ligand for CD36 (transmembrane glycoprotein or scavenger receptor B2), exhibits selective binding to CD36 over human serum albumin (HSA), IgG, and CD44 in cell-free assays at 1 mM concentration. P... |
